Longer tamoxifen use cuts breast cancer deaths

Breast cancer patients taking the drug tamoxifen can cut their chances of having the disease come back or kill them if they stay on the pills for 10 years instead of five years as doctors recommend now, a major study finds.

The results could change treatment, especially for younger women. The findings are a surprise because earlier research suggested that taking the hormone-blocking drug for longer than five years didn’t help and might even be harmful.

In the new study, researchers found that women who took tamoxifen for 10 years lowered their risk of a recurrence by 25 percent and of dying of breast cancer by 29 percent compared to those who took the pills for just five years.

In absolute terms, continuing on tamoxifen kept three additional women out of every 100 from dying of breast cancer within five to 14 years from when their disease was diagnosed. When added to the benefit from the first five years of use, a decade of tamoxifen can cut breast cancer mortality in half during the second decade after diagnosis, researchers estimate.

Some women balk at taking a preventive drug for so long, but for those at high risk of a recurrence, “this will be a convincer that they should continue,” said Dr. Peter Ravdin, director of the breast cancer program at the UT Health Science Center in San Antonio.

He reviewed results of the study, which was being presented Wednesday at a breast cancer conference in San Antonio and published by the British medical journal Lancet.

About 50,000 of the roughly 230,000 new cases of breast cancer in the United States each year occur in women before menopause. Most breast cancers are fueled by estrogen, and hormone blockers are known to cut the risk of recurrence in such cases.

Tamoxifen long was the top choice, but newer drugs called aromatase inhibitors — sold as Arimidex, Femara, Aromasin and in generic form — do the job with less risk of causing uterine cancer and other problems.

But the newer drugs don’t work well before menopause. Even some women past menopause choose tamoxifen over the newer drugs, which cost more and have different side effects such as joint pain, bone loss and sexual problems.

The new study aimed to see whether over a very long time, longer treatment with tamoxifen could help.

Dr. Christina Davies of the University of Oxford in England and other researchers assigned 6,846 women who already had taken tamoxifen for five years to either stay on it or take dummy pills for another five years.

Researchers saw little difference in the groups five to nine years after diagnosis. But beyond that time, 15 percent of women who had stopped taking tamoxifen after five years had died of breast cancer versus 12 percent of those who took it for 10 years. Cancer had returned in 25 percent of women on the shorter treatment versus 21 percent of those treated longer.

Tamoxifen had some troubling side effects: Longer use nearly doubled the risk of endometrial cancer. But it rarely proved fatal, and there was no increased risk among premenopausal women in the study — the very group tamoxifen helps most.

“Overall the benefits of extended tamoxifen seemed to outweigh the risks substantially,” Dr. Trevor Powles of the Cancer Centre London wrote in an editorial published with the study.

The study was sponsored by cancer research organizations in Britain and Europe, the United States Army, and AstraZeneca PLC, which makes Nolvadex, a brand of tamoxifen, which also is sold as a generic for 10 to 50 cents a day. Brand-name versions of the newer hormone blockers, aromatase inhibitors, are $ 300 or more per month, but generics are available for much less.

The results pose a quandary for breast cancer patients past menopause and those who become menopausal because of their treatment — the vast majority of cases. Previous studies found that starting on one of the newer hormone blockers led to fewer relapses than initial treatment with tamoxifen did.

Another study found that switching to one of the new drugs after five years of tamoxifen cut the risk of breast cancer recurrence nearly in half — more than what was seen in the new study of 10 years of tamoxifen.

“For postmenopausal women, the data still remain much stronger at this point for a switch to an aromatase inhibitor,” said that study’s leader, Dr. Paul Goss of Massachusetts General Hospital. He has been a paid speaker for a company that makes one of those drugs.

Women in his study have not been followed long enough to see whether switching cuts deaths from breast cancer, as 10 years of tamoxifen did. Results are expected in about a year.

The cancer conference is sponsored by the American Association for Cancer Research, Baylor College of Medicine and the UT Health Science Center.

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Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP

Health News Headlines – Yahoo! News

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Philippines death toll climbs, hundreds still missing after typhoon

NEW BATAAN, Philippines (Reuters) - Blocked roads and severed communications in the southern Philippines frustrated rescuers on Wednesday as teams searched for hundreds of people missing after the strongest typhoon this year killed at least 283 people.

Typhoon Bopha, with central winds of 120 kph (75 mph) and gusts of up to 150 kph (93 mph), battered beach resorts and dive spots on Palawan island on Wednesday but it was weakening as it moved west.

Hardest hit was the southern island of Mindanao, where Bopha made landfall on Tuesday. It triggered landslides and floods along the coast and in farming and mining towns inland.

Interior Minister Manuel Roxas said 300 people were missing.

"Entire families were washed away," Roxas, who inspected the disaster zone, told reporters.

Most affected areas were cut off by destroyed roads and collapsed bridges and army search-and-rescue teams were being flown in by helicopter.

Power was cut and communications were down.

According to tallies provided by the military and disaster agency officials, 283 people were killed.

Thousands of people were in shelters and officials appealed for food, water and clothing. Dozens of domestic flights were suspended on Wednesday.

The governor of the worst-hit province, Compostela Valley, in Mindanao said waves of water and mud came crashing down mountains and swept through schools, town halls and clinics where huddled residents had sought shelter.

The death toll in the province stood at 160. In nearby Davao Oriental province, where Bopha made landfall, 110 people were killed.

"The waters came so suddenly and unexpectedly, and the winds were so fierce," the Compostela Valley governor, Arthur Uy, told Reuters by telephone.

He said irrigation reservoirs on top of mountains had given way sending large volumes of water down to the valleys. Torrential rain often triggers landslides down slopes stripped of their forest cover.

Damage to agriculture and infrastructure in the province was extensive, Uy said.

STUNNED

Corn farmer Jerry Pampusa, 42, and his pregnant wife were marooned in their hut but survived.

"We were very scared," Pampus said. "We felt we were on an island because there was water everywhere."

Another survivor, Francisco Alduiso, said dozens of women and children who had taken shelter in a village centre, had been swept away.

"We found some of the bodies about 10 km (6 miles) away," Alduisa told Reuters. The only building left standing in his village was the school.

Another survivor, Julius Julian Rebucas, said his mother and brother disappeared in a flash flood.

"I no longer have a family," a stunned Rebucas said.

An army commander said two dozen people had been pulled from the mud in one area and were being treated in hospital.

About 20 typhoons hit the Philippines every year, often causing death and destruction.

Almost exactly a year ago, Typhoon Washi killed 1,500 people in Mindanao.

(Additional Reporting by Rosemarie Francisco and Manny Mogato; Editing by Robert Birsel)

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Officials: NATO to decide on missiles for Turkey

BRUSSELS (AP) — NATO foreign ministers are expected to approve Turkey‘s request for Patriot anti-missile systems to bolster its defense against possible strikes from neighboring Syria.

NATO foreign ministers are meeting on Tuesday and Wednesday in Brussels. Parliaments in both nations must approve the deployment, which would also involve several hundred soldiers.

Ankara, which has been highly supportive of the Syrian opposition, wants the Patriots to defend against possible retaliatory attacks by Syrian missiles carrying chemical warheads. NATO leaders have repeatedly said they would provide any assistance Turkey needs.

Europe News Headlines – Yahoo! News

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Student group to go to court over Facebook privacy policy

VIENNA (Reuters) – An Austrian student group plans to go to court in a bid to make Facebook Inc, the world’s biggest social network, do more to protect the privacy of its hundreds of millions of members.

Campaign group europe-v-facebook, which has been lobbying for better data protection by Facebook for over a year, said on Tuesday it planned to go to court to appeal against decisions by the data protection regulator in Ireland, where Facebook has its international headquarters.

The move is one of a number of campaigns against the giants of the internet, which are under pressure from investors to generate more revenue from their huge user bases but which also face criticism for storing and sharing personal information.

Internet search engine Google, for example, has been told by the European Union to make changes to its new privacy policy, which pools data collected on individual users across its services including YouTube, gmail and social network Google+, and from which users cannot opt out.

Europe-v-facebook has won some concessions from Facebook, notably pushing it to switch off its facial recognition feature in Europe.

But the group said on Tuesday the changes did not go far enough and it was disappointed with the response of the Irish Data Protection Commissioner (DPC), which had carried out an audit after the campaign group filed numerous complaints.

Facebook, due to hold a conference call later on Tuesday to answer customer concerns about its privacy policy, said its data protection policies exceeded European requirements.

“The latest Data Protection report demonstrates not only how Facebook adheres to European data protection law but also how we go beyond it, in achieving best practice,” a Facebook spokesman said in an emailed comment.

“Nonetheless we have some vocal critics who will never be happy whatever we do and whatever the DPC concludes.”

LOSING PATIENCE

Europe-v-facebook founder Max Schrems, who has filed 22 complaints with the Irish regulator, said more than 40,000 Facebook users who had requested a copy of the data Facebook was holding on them had not received anything several months after making a request.

“The Irish obviously have no great political interest in going up against these companies because they’re so dependent on the jobs they create,” Schrems told Reuters.

Gary Davies, Ireland’s deputy data protection commissioner, denied Facebook’s investment in Ireland had influenced regulation of the company.

“We have handled this in a highly professional and focused way and we have brought about huge changes in the way Facebook handles personal data,” he told Reuters.

Schrems also questioned why Facebook had only switched off facial recognition for users in the European Union, even though Ireland is the headquarters for all of Facebook’s users outside the United States and Canada.

Facebook is under pressure to reverse a trend of slowing revenue growth by selling more valuable advertising, which requires better profiling of its users.

Investors are losing patience with the social network, whose shares have dropped 40 percent in value since the company’s record-breaking $ 104 billion initial public offering in May.

Last month, Facebook proposed to combine its user data with that of its recently acquired photo-sharing service Instagram, loosen restrictions on emails between its members and share data with other businesses and affiliates that it owns.

Facebook is also facing a class-action lawsuit in the United States, where it is charged with violating privacy rights by publicizing users’ “likes” without giving them a way to opt out.

A U.S. judge late on Monday gave his preliminary approval to a second attempt to settle the case by paying users up to $ 10 each out of a settlement fund of $ 20 million.

Europe-v-facebook said it believed its Irish battle had the potential to become a test case for data protection law and had a good chance of landing up in the European Court of Justice.

Schrems said the case could cost the group around 100,000 euros ($ 130,000), which it hoped to raise via crowd-funding – money provided by a collection of individuals – on the Internet.

(Additional reporting by Conor Humphries in Dublin; Editing by Mark Potter)

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“Boardwalk Empire” creator on legalizing drugs and making Nucky likeable again

NEW YORK (TheWrap.com) – The prohibition drama “Boardwalk Empire” wrapped its spectacular third season Sunday night just weeks after the states of Colorado and Washington voted to legalize marijuana.

To “Boardwalk” creator Terence Winter, who has immersed himself in the history of prohibition to research his gangster epic, the votes feel like a move in the right direction.

“It’s great. I think they should legalize drugs in general,” Winter told TheWrap. “The war on drugs is clearly not working, and I think they should take the profit motive out of being a drug dealer. And maybe kids will go to college and do something else.”

Winter, who reassembled his writers a few weeks ago to begin work on the show’s fourth season, talked to us about whether they ever go out of their way to slow down the action, making Nucky Thompson (Steve Buscemi) likable again, and whether things are worse today than they were in the 1920s.

TheWrap: Is ‘Boardwalk’ making a case for drug legalization?

Winter: Well, I think history made it for us with prohibition. We’re just reflecting the reality of how it went down. I’m not trying to bend the reality or the truth of what happened. It clearly didn’t work. I don’t think people were more disposed to drink when alcohol was legal.

Actually, it had the opposite effect. Women didn’t start drinking until prohibition was enacted and college students didn’t start drinking until prohibition was enacted. Leaving the mystery aside might have had a better impact on the country – keeping it legal. In my personal opinion I don’t think making drugs legal would make anybody more likely to become a heroin addict, for example.

This is going to sound strange, but I mean it as a compliment. “Boardwalk” has a way of lulling you into looking at the costumes, and listening to the dialogue, and marveling at how pretty everything is. There are times when I almost want to nod off, it’s so comforting – and then suddenly someone gets set on fire. I feel you’re making a conscious effort to use boredom to really shock us at other times. Do you ever put in a scene that’s deliberately slow?

No, we don’t. I would disagree and say – slow or boring – there is dialogue that needs to be attended to and I think you need to pay attention to what’s going on. The pacing can sometimes be slower than certainly an action scene or a scene with incredible violence. Because we have such wide-ranging characters and such wide-ranging circumstances, some things might seem slower by comparison.

Obviously a scene involving a political figure or Margaret’s storyline, as opposed to something Al Capone is doing, is just by the very nature of it going to feel slow. But no, none of it is done by design.

I mean it in a good way. If you think things are slowing down, they’re not. It’s almost a trick.

The audience is so wide-ranging, too. We have people who can’t stand the violence and they’re much more entertained by the family stuff. One person’s slow is another person’s fascinating.

With the final episodes we got to see Nucky become really likable again. He’s always been generous, but at times he seemed a little too caught up in himself to care about the people around him. Was there an effort to make him a good guy again?

One of the points of this season is that he does get caught up in himself. That all comes home to visit in a big way in episode 11. He doesn’t know anything about Eddie Kessler the guy who works really closely with him. He doesn’t know if he has a family. He doesn’t know Chalky White’s phone number. It becomes apparent that he’s spent way too much time concerned with himself and his own affairs.

If you depict any character honestly, and show all of their colors, you’re going to find something relatable or likeable with anybody. And that’s certainly the truth with Al Capone or Luciano or Tony Soprano or any other famous character.

And certainly Steve Buscemi has an inherent likable quality to him. So when you add that to the mix you can’t help but like the guy.

Imagery is so important to the show, and I feel like at one point this season you did something just because it was gorgeous. When Billie changes her hair color to blonde, was there any reason to do that besides how incredible it looked in the explosion?

Well, she was sort of finally coming to terms with who she really was. That was the episode where she dropped the façade of Billie Kent and told Nucky her real name. She was going through a metamorphosis and that sort of illustrated that a little bit. They were sort of not pretending with each other any more.

Is Billie a natural blonde?

That color wasn’t natural. She wasn’t being Billie Kent that night. She was being the real person underneath. … But I agree it did look great in the explosion. Meg Chambers Steedle, who plays Billie Kent, is absolutely one of those people the camera just falls in love with. Unfortunately the context was terrible. But it was extremely cinematic.

Harrow kind of became the hero of the show this season. His scene of taking down the entire house full of gangsters: Wow. We’ve always been fascinated with the character and for me this season I was more interested in seeing who he is as a person and seeing him take that journey and fall in love and really explore that side of him. Given the way the story was, we knew it would end in violence.

But following the trajectory from the end of season 2, we knew this guy was very loyal to Jimmy and Angela and we knew he would stick around and take care of that kid. And of course Gillian being who she is, it wasn’t going to end well.

Is Gillian kaput at this point? The last time we saw her she was in a heroin daze, and she’s kind of lost everything.

She will be back on the show. She’s certainly still alive.

Is there anybody on the show you think you can’t kill?

Nope. Everybody’s up for grabs and that’s from the top on down. Anything can happen.

We hear so much about how much trouble our country is in. Do you think things are worse than they were in the 1920s?

No, and if anything, reading about how bad things were in the 1920s is strangely comforting in terms of how we think about things today. The level of corruption and the whole idea of going to hell in a hand basket is certainly nothing new. You look back and think, this pales in comparison. I think the more things change the more they stay the same.

TV News Headlines – Yahoo! News

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Scientists find gene link to teenage binge drinking

LONDON (Reuters) – Scientists have unpicked the brain processes involved in teenage alcohol abuse and say their findings help explain why some young people have more of a tendency to binge drink.

A study published in the Proceedings of National Academy of Sciences (PNAS) journal found that a gene known as RASGRF-2 plays a crucial role in controlling how alcohol stimulates the brain to release dopamine, triggering feelings of reward.

“If people have a genetic variation of the RASGRF-2 gene, alcohol gives them a stronger sense of reward, making them more likely to be heavy drinkers,” said Gunter Schumann, who led the study at King’s College London’s Institute of Psychiatry.

Alcohol and other addictive drugs activate the brain’s dopamine systems, which induces feelings of pleasure and reward.

Worldwide, some 2.5 million people die each year from the harmful use of alcohol, accounting for about 3.8 percent of all deaths, according to the World Health Organisation.

Recent studies also carried out by scientists at the IoP have found that RASGRF-2 is a risk gene for alcohol abuse, but until now the mechanism involved in the process was not clear.

For this study, scientists initially looked at mice who had been modified to have the RASGRF2 gene removed, to see how they reacted to alcohol. They found the lack of RASGRF-2 was linked to a significant reduction in alcohol-seeking activity.

They also discovered that when the mice did consume alcohol, the absence of RASGRF-2 reduced the activity of dopamine-releasing neurons in a region of the brain called the ventral tegmental area (VTA) – preventing the brain from releasing dopamine and limiting any sense of reward.

The team then analyzed brain scans of 663 14-year old boys and found that when they were anticipating a reward in a mental test, those with genetic variations to the RASGRF2 gene had more activity in an area of the brain closely linked to the VTA and also involved in dopamine release.

This suggests people with a genetic variation on the RASGRF-2 gene release more dopamine when anticipating a reward, and hence derive more pleasure from it, the scientists said.

To confirm the findings, the team analyzed drinking behavior from the same group of boys two years later when many of them had already begun drinking frequently.

They found that those with the RASGRF-2 gene variation drank more often at the age of 16 than those without it.

“People seek out situations which fulfill their sense of reward and make them happy, so if your brain is wired to find alcohol rewarding, you will seek it out,” Schumann said in a statement about the research. “We now understand the chain of action: how our genes shape this function in our brains and how that, in turn, leads to human behavior.”

Experts writing in The Lancet journal in February said up to 210,000 people in England and Wales will be killed prematurely by alcohol in the next 20 years, with a third of those preventable deaths due to liver disease alone.

(Reporting by Kate Kelland)

Medications/Drugs News Headlines – Yahoo! News

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Does the GOP need a religious retreat?

(Photo by Brandon Thibodeaux/Getty Images)

It's no surprise that Florida Sen. Marco Rubio took heat for an interview he gave to GQ magazine this month: Departing from scientific consensus, the rising Republican star refused to state whether the Earth is billions of years old or a few thousand, as many fundamentalist Christians believe.

What no one expected was the rebuke from televangelist and longtime Christian conservative leader Pat Robertson, dismissing theories of a "young Earth."

"If you fight science, you are going to lose your children," Robertson said last week during an appearance on the Christian Broadcast Network, the television empire he founded three decades ago.

Robertson wasn't directly speaking to Rubio, but the senator and others in his party might heed the advice. Viewed by many voters as anti-science and too conservative on social issues such as gay marriage, the Republican Party is in danger of losing young and less religious voters for years to come.

In a post-election breakdown by the Public Religion Research Institute, the Obama religious coalition mirrors the demographics of 18-29 year olds, whereas Romney's mirrors those of voters aged 65 and up.

On Nov. 6, as President Barack Obama won a narrow but clear victory over Mitt Romney, voters in four states expressed support for gay marriage. Anti-abortion candidates lost in several states, including Senate contenders Todd Akin of Missouri and Richard Mourdock of Indiana, both of whom stirred outrage from their remarks on rape.

Many experts believe these developments point in part to a decisive shift in the religious makeup of the country, one that could make or break a GOP comeback.

"The way Republicans speak is turning off the youngest, fastest growing groups in the country—Latinos and significantly, the unchurched, those with no religious affiliation," said Mark Rozell, a public policy professor at George Mason University who studies religion and politics. "To them, the Republicans are proselytizing."

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Since the 1980s, organizations like Focus on the Family, the Moral Majority and the Christian Coalition cemented religious conservatives as visible and potent force in the Republican coalition and enforced discipline on social issues such as abortion and gay rights. But now, the religious landscape is changing beneath their feet.

Studies suggest the number of unchurched has doubled in the past two decades and shot up by 25 percent in the last four years. The shift has taken place across the country and across economic classes, most notably among the young; one fifth of adults and one third of Americans under thirty now declare themselves religiously unaffiliated.

The new and expanding group of unchurched voters overwhelmingly support same sex-marriage and legal abortion, and so they gravitate toward the Democratic Party.

"It's clearly a concern—we have a lot of work to do," said Gary Marx, executive director of the Faith and Freedom Coalition, which worked to boost turnout among Catholics and evangelical voters.

The group, founded by conservative Christian activist Ralph Reed, helped deliver more religious voters to the polls this year than in 2008, but such efforts couldn't deliver a Romney victory.

In a press release following the election, Reed acknowledged that minorities and the young—and therefore, he might have added, the unchurched—made the difference for Obama.

Marx and his colleagues insist they aren't especially concerned about the growing secularization of young voters. They are primarily looking to diversify the GOP's religious coalition, Marx said.

To close the Latino gap, Marx says conservative activists are planning a major outreach effort to evangelical Hispanics and to Hispanic Catholics who attend Mass.

"We are casting a wider net—the politics of addition, not subtraction," Marx said, adding that Latinos and other minorities have been attracted to many conservative positions like education reform.

Marx pointed to Georgia, where Hispanic and black voters supported a state amendment allowing the state government to set up charter schools.

Marx also suggested the Democratic advantage with young minority voters was "candidate-centric" — a reflection of Obama's unique status as the first black president.

But the problem may run deeper, into the Republican base: There is growing evidence that young evangelicals are simply less interested in politicizing hot-button issues.

"Young evangelicals don't look at the country as a battlefield, but rather a mission field," says James Wilcox, a George Mason University political science professor. "They're are less scared than their forbearers: They see the 'War on Religion' narrative as nonsense; they see churches thriving, the outlets they have, and the extent of religious pluralism in this country."

The new generation sees community activism, rather than electoral politics, as the means for their faith to shape the world, Wilcox argues. They may disagree with liberals about same-sex marriage, but they also believe that states have the right to determine such policies.

Many younger evangelicals are also serious about addressing climate change, even as many high-profile conservatives have expressed doubt about whether climate change is real—with nominee Mitt Romney cracking jokes about it at this year's Republican National Convention.

None of this means the influence of religious conservatives on Republican politics is set to disappear. But it is most certainly about to change.

Between the rise of the unchurched and the moderation of young religious conservatives, experts say, a smaller movement may emerge — one that retains its current zeal but carries less sway over the selection of GOP nominees. Or the movement could retain its power by successfully diversifying and coming up with a new way to talk to voters.

"We plan to reach out with a softer, pro-family agenda—less emphasis on the sexual points, more talk about family," Marx of the Faith and Freedom Coalition said. He also said activists would develop a "forward-looking" policy agenda akin to President George W. Bush's "compassionate conservatism."

But at the same time, Marx believes that some of that message already has been lifted by social liberals: "It is true that gay rights activists have stolen that language of 'family' we've used successfully, and now use it for their purposes."

One way for religious conservatives to start again, Rozell said, would be to return the favor and take a tip from two much-heralded communicators: Presidents Ronald Reagan and Bill Clinton.

"Successful politicians can speak two languages, even if it's hard to do," Rozell said. Reagan did it, addressing both the Christian right and a largely secular small-government audience. Often times it's a shift in rhetoric rather than policy."

Rozell cited Republican Gov. Bob McDonnell of Virginia, a strong social conservative, who has maintained his popularity by using language that appeals to both religious and secular audiences.

Another strategy would be to borrow from the vocabulary of the other team, as Bill Clinton did when he co-opted the rhetoric of religious conservatives to crack down on the culture of sex and violence on TV.

"Put aside this talk of wars," Rozell says, "Republicans could easily adopt the rhetoric of "rights" and "tolerance" that liberals currently own, to speak to secular types about the value of pluralism and religious conscience."

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Gunmen assassinate peasant leader in Paraguay

ASUNCION, Paraguay (AP) — Gunmen murdered one of the surviving leaders of a peasant movement whose land dispute with a powerful politician prompted the end of Fernando Lugo‘s presidency last June.

Vidal Vega, 48, was hit four times early Saturday by bullets from a 12-gauge shotgun and a .38-caliber revolver fired by two unidentified men who sped away on a motorcycle, according to an official report prepared at the police headquarters in the provincial capital of Curuguaty.

A friend, Mario Espinola, told The Associated Press that Vega was shot down when he stepped outside to feed his farm animals.

Vega was among the public faces of a commission of landless peasants from the settlement of Yby Pyta, which means Red Dirt in their native Guarani language.

He had lobbied the government for many years to redistribute some of the ranchland that Colorado Party Sen. Blas Riquelme began occupying in the 1960s.

By last May, the peasants finally lost patience and moved onto the land. A firefight during their eviction on June 15 killed 11 peasants and six police officers, prompting the Colorado Party and other leading parties to vote Lugo out of office for allegedly mismanaging the dispute.

Twelve suspects, nearly all of them peasants from Yby Pyta, have been jailed without formal charges since then on suspicion of murdering the officers, seizing property and resisting authority. The prosecutor had six months to develop the case and will present his findings Dec. 16.

Vega was expected to be a witness at the criminal trial, since he was among the few leaders who weren’t killed in the clash or jailed afterward.

He wasn’t charged because he was away getting supplies when the violence erupted at the settlement erected by the peasants inside Riquelme’s ranch, the Naranjaty Commission’s secretary, Martina Paredes, told the AP.

“We think he was assassinated by hit men who were sent, we don’t know by whom, perhaps to frighten us and frustrate our fight to recover the state lands that were illegally taken by Riquelme,” she said.

Riquelme, who died of natural causes about a month after the battle in June, occupied the land during the dictatorship of Alfredo Stroessner, whose government gave away land for free to anyone willing to put it to productive use.

A local court in Curuguaty upheld Riquelme’s claim to the land years later. Lugo’s government later sought to overturn the decision, but the case remains tied up in court.

Latin America News Headlines – Yahoo! News

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Hands-On With the World-Changing $40 Tablet

Aakash2

The Aakash2 is available for $ 40.41 (2,263 rupees), but the government of India will subsidize half the cost for schoolchildren. The tablet is conceived as a tool to help end India‘s rampant illiteracy. Aakash2 will bring school-age children connectivity and unprecidented access to books.

Click here to view this gallery.

[More from Mashable: Zynga Holiday Campaign Turns Virtual Goods Into Real-World Donations]

The Aakash2, the second generation of the monumental, ultra-cheap tablet from Indian manufacturer DataWind, arrived in the U.S. Wednesday, with a welcome at the U.N. Headquarters in New York.

DataWind is hoping to prove to the tech and development communities that the $ 40 Aakash2 is faster than its predecessor, the original Aakash, which was much-criticized for its glacial processor.

[More from Mashable: The Top 5 Gadget Innovations of 2012]

You may be wondering what exactly you can put in a tablet that sells for just $ 40.41. The 7-inch Android-powered device has 512 MB of RAM, a 1 Ghz processor, 4 GB of flash memory, a multi-touch capacitative screen, front-facing camera, an internal microphone and speakers. The Aakash2 includes a USB hub, an adapter cable, a wall charger and a 12-month warranty.

Sunseet Singh Tuli, DataWind’s CEO and the visionary behind the tablet, points out that Aakash2 wasn’t conceived for the same demographic as the iPad. It’s developed out of the requisite “frugal innovation” that guides India and the developing world.

“Frugal innovation isn’t about creating an iPad killer, it’s about creating an iPad for him,” said Tuli, pointing to a presentation slide of a lower-class man who’s primary motivation is to receive an education. “This is not a straight commerce effort — it’s an educational effort.”

Even the tablet’s name — Aakash, which means sky in Hindi — references that it was created to awaken students’ potential. The government of India has committed to subsidize 50% of the cost of the device for students, making it available for roughly $ 20.

According to DataWind, the technological breakthrough of the Aakash2, which is why the device can be made so inexpensively, is twofold. First, much of its memory and processing power is transfered to backend servers. Second, the parallel processing environment speeds the user experience in remote areas and congested networks.

The Aakash2 also eliminates hardware features deemed unnecessary for the target audience, such as bluetooth and the HDMI interface. It uses open source software to cut costs, as well.

“This tablet seeks to empower the world’s neediest and bridges the digital divide within our society,” said Hardeep Singh Puri, India’s permanent representative to the U.N. at the launch event. “To us, Aakash2 is the epitome of such high end innovation and excellence.”

The Aakash to was designed and developed in Canada, though it was conceived, assembled and programmed in India. DataWind and the Indian government have received criticism because the process is not entirely domestic, though both said they are committed to moving more of the production process to India when cost allows.

The Indian government has committed to equipping all 220 million students in the country with low-cost computing devices and Internet access over the next five years. To put that number in perspective, just 250,000 tablets were sold in India in 2011. It will cost $ 1.6 billion per year at the rate of equipping 40 million students for each of the next five years. The national government has committed to covering half the cost — $ 800 million per year — and will count on state governments and institutions to cover the remaining 50% of costs. Though it sounds like a daunting figure, $ 800 million is only 5% of India’s annual education budget.

“More and more schools in some of the most impoverished areas are using technology, text messaging and mobile applications to enhance the quality of education and open new doors,” said U.N. Secretary General Ban Ki-moon on Wednesday. “Our challenge is to leverage the power of technology and bridge the digital divide.”

During Wednesday’s event at the U.N., Tuli presented Ki-moon with an Aakash2 tablet for each of the U.N. ambassadors.

Not surprisingly, other countries throughout the developing world have noticed the Aakash tablet’s potential. Thailand, Turkey, Sri Lanka, Bolivia, Honduras, Nicaragua, Brazil and Panama have all expressed interest in bringing the low-cost tablet to their students.

“The next arms race is to equip our children with knowledge and information,” Tuli said.

If you’re wondering when you can get your hands on an Aakash2 in the U.S., DataWind plans to begin selling the device in the U.S. in early 2013.

Do you think this low-cost tablet has the power to bridge the digital divide and combat illiteracy? Let us know in the comments.

This story originally published on Mashable here.

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“Searching for Sugar Man” wins Producers Guild documentary nomination

LOS ANGELES (TheWrap.com) – “Searching for Sugar Man” is the best-known of the five films whose producers have been nominated for documentary motion pictures by Producers Guild of America, which announced its nominations on Friday.

Malik Bendjelloul’s film about the rediscovery of ’70s recording artist Rodriguez joined a slate of nominees that also includes Jon Shenk’s doc about the ousted president of the Maldives, “The Island President”; Marius A. Merkevicius‘ story of the 1992 Lithuanian Olympic basketball team, “The Other Dream Team”; Dror Moreh’s chronicle of some members of the Israeli intelligence services, “The Gatekeepers”; and Aaron Yeger’s film about the Roma (gypsies) in Europe, “A People Uncounted.”

The PGA bypassed number of the year’s high-profile docs, including “Bully,” “The Queen of Versailles,” “The Imposter,” “Samsara,” “West of Memphis” and “The Invisible War.”

Of the guild’s choices, only “Sugar Man” was also nominated in the top category at the IDA Awards and the Cinema Eye Honors, the two major awards in the documentary field.

The PGA release:

LOS ANGELES, CA (November 30, 2012) – The Producers Guild of America (PGA) announced today the Documentary Motion Picture nominees that will advance in the voting process for the 24th Annual Producers Guild Awards.

The nominated films, listed below in alphabetical order, are:

A PEOPLE UNCOUNTED

THE GATEKEEPERS

THE ISLAND PRESIDENT

THE OTHER DREAM TEAM

SEARCHING FOR SUGAR MAN

All other nominations for the 2013 Producers Guild Award categories will be announced on January 3, 2013, along with the individual producers.

All 2013 Producers Guild Award winners will be announced on January 26, 2013 at the Beverly Hilton Hotel. This year, the Producers Guild will also award special honors to Bob and Harvey Weinstein, J.J. Abrams, Tim Bevan and Eric Fellner and Russell Simmons, among others. The 2013 Producers Guild Awards Chair is Michael De Luca.

In 1990, the Producers Guild held the first-ever Golden Laurel Awards, which were renamed the Producers Guild Awards in 2002. Richard Zanuck and Lili Fini Zanuck took home the award for Best Produced Motion Picture for DRIVING MISS DAISY, establishing the Guild’s awards as a bellwether for the Oscars. Last year, the PGA awarded THE ARTIST with its Darryl F. Zanuck Producer of the Year Award in Theatrical Motion Pictures, marking the fifth consecutive year the Producers Guild has presaged the Academy of Motion Picture’s choice.

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